Biocatalysts and methods for hydroxylation of chemical compounds

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United States of America

PATENT NO 12247234
APP PUB NO 20230227875A1
SERIAL NO

18059949

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Abstract

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The present disclosure provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.

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Patent Owner(s)

  • CODEXIS INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bong, Yong Koy Singapore, SG 30 53
Cabirol, Fabien L Dusseldorf, DE 8 36
Chen, Haibin Beijing, CN 96 1781
Collier, Steven J Concord, US 113 378
Gohel, Prafulchandra Anupam Bekasi, ID 6 32
Hong, Yang Singapore, SG 25 190
Li, Tao Cincinnati, US 743 4256
Moore, Jeffrey C Westfield, US 102 1274
Quintanar-Audelo, Martina Edinburgh, GB 11 40
Smith, Derek Singapore, SG 126 2816

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