Highly efficient anti-TFPI antibody composition

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12247082
APP PUB NO 20220025067A1
SERIAL NO

17276276

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure relates to a pharmaceutical highly efficient anti-TFPI antibody composition including an anti-TFPI antibody for treating hemophilia, in which the content of HCP in a drug substance is less than 10.0 ng/mg, and the content of LPA in the drug substance or the drug product is less than 1.0 ng/mg. According to the present disclosure, a highly efficient anti-TFPI antibody composition having very low contents of HCP and LPA may be provided by providing a separation/purification process capable of minimizing anti-TFPI antibody polymer generation, and may be effectively used for the treatment of antibody-induced hemophilia patients and for the prevention of blood coagulation disease.

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Patent Owner(s)

  • GREEN CROSS CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Min Jung Yongin-si, KR 216 932
Kim, Yuna Yongin-si, KR 31 59
Park, Ji Yoon Yongin-si, KR 27 170
Song, Haeng Eun Yongin-si, KR 1 0
Yeo, Geun Hye Yongin-si, KR 2 1

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