Nucleic acids encoding modified FGF-21 polypeptides, vectors and cells containing, and use thereof

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United States of America

PATENT NO 12247058
APP PUB NO 20220185856A1
SERIAL NO

17555633

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Abstract

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Nucleic acids encoding modified FGF-21 polypeptides, optionally containing at least one non-codon encoding a naturally-encoded amino acid, and vectors and cells containing are provided. These nucleic acids can be used to express the modified FGF-21 polypeptide encoded thereby. The expressed FGF-21 polypeptides may be used as therapeutics, e.g., in the treatment of diseases associated with fibrosis.

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Patent Owner(s)

  • BRISTOL MYERS SQUIBB COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Camphausen, Ray Wayland, US 59 1495
Christian, Rose C Hopewell, US 8 38
Cohen, Daniel New York, US 183 2404
Krupinski, John Flemington, US 6 38
Lipovsek, Dasa Pepperell, US 81 1800
Morin, Paul E Pennington, US 27 301
Mukherjee, Ranjan Churchville, US 37 3580
Reilly, Timothy P New Hope, US 6 38

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