Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-a][1,4]diazepines

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United States of America

PATENT NO 12246196
APP PUB NO 20220395579A1
SERIAL NO

17849688

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Abstract

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Provided are novel antibody-pyrrolodiazepine derivative and novel antibody-pyrrolodiazepine derivative conjugates, as well as methods of using the same, and a novel CLDN6 and/or CLDN9 antibody. The disclosed compounds are of the class of alkyl benzene sulfonyl ureas, useful as oral anti-diabetics, and include substituted benzo[e]pyrrolo[1,2-α][1,4]diazepine.

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Patent Owner(s)

Patent OwnerAddress
DAIICHI SANKYO COMPANY LIMITED3-5-1 NIHONBASHI HONCHO CHUO-KU TOKYO 1038426 ?1038426

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ashida, Shinji Tokyo, JP 26 190
Doi, Fuminao Tokyo, JP 9 1
Hamada, Hirofumi Tokyo, JP 31 166
Harada, Naoya Tokyo, JP 9 1
Hayakawa, Ichiro Tokyo, JP 18 98
Iwamoto, Mitsuhiro Tokyo, JP 17 25
Masuda, Takeshi Tokyo, JP 280 2493
Meguro, Masaki Tokyo, JP 14 49
Nakada, Takashi Tokyo, JP 26 334
Nakamura, Kensuke Tokyo, JP 65 483
Okajima, Daisuke Tokyo, JP 23 72
Ota, Yusuke Tokyo, JP 103 642
Terauchi, Tomoko Tokyo, JP 13 9
Toda, Narihiro Tokyo, JP 17 40
Uchida, Hiroaki Tokyo, JP 40 227

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