Omega-alicyclic tunicamycins and analogs

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United States of America

PATENT NO 12245589
APP PUB NO 20230320354A1
SERIAL NO

17718981

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Abstract

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The invention relates to new tunicamycin structures comprising N-acyl groups metabolically integrated into the terminus of the TUN via the Streptomyces branched chain fatty acid pathways and variants thereof, and methods of preparing such new tunicamycin structures. The invention further relates to antibacterial compositions comprising such new tunicamycin structures, and methods for using such antibacterial compositions for killing Gram-positive bacteria.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bannantine, John P Ames, US 13 72
Hartman, Trina M Peoria, US 1 0
Jackson, Michael A Morton, US 16 98
Price, Neil P Edelstein, US 12 11

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