N-terminal scFv multispecific binding molecules

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United States of America

PATENT NO 12240907
APP PUB NO 20210130477A1
SERIAL NO

17088918

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Abstract

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Multispecific binding molecules (MBMs) comprising an N-terminal scFv, a first Fab and a second Fab, MBM conjugates comprising the MBMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the MBMs and MBM conjugates, methods of using the MBMs, MBM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the MBMs, cells engineered to express the MBMs, and methods of producing MBMs.

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Patent Owner(s)

  • REGENERON PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lee, Ann-Hwee Ardsley, US 6 58
Lin, Chia-Yang Scarsdale, US 65 112
Shen, Yang Scarsdale, US 112 384
Yang, Yan Mamaroneck, US 263 1576

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