Microfluidic device and diagnostic methods for allergy testing based on detection of basophil activation

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12239982
APP PUB NO 20210394183A1
SERIAL NO

17292782

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Devices, methods, and kits are provided for allergy testing based on basophil activation in a blood sample. Susceptibility of an individual to an allergic reaction to an allergen is detected by collecting a blood sample from the individual and assaying for activation of basophils in response to stimulation with an allergen. In particular, a microfluidic device is provided for automating the assay for detecting basophil activation as an indication of the susceptibility of an individual to an allergic reaction as well as kits containing such a device and diagnostic methods for using such a device for allergy testing. Additionally, such a microfluidic device can be adapted for multiplexed detection of allergic responses to multiple allergens by performing assays in parallel to detect the basophil responses to each allergen.

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Patent Owner(s)

  • THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bunning, Bryan J San Mateo, US 1 0
Castano, Nicolas Stanford, US 2 0
Cordts, Seth Palo Alto, US 1 0
Lyu, Fengjiao Stanford, US 2 20
Nadeau, Kari C Los Altos Hills, US 20 390
Tang, Sindy K Y Palo Alto, US 7 0

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