Piperazine amide derivative, preparation method therefor, and use thereof in medicine

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United States of America

PATENT NO 12234222
APP PUB NO 20220177450A1
SERIAL NO

17602758

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Abstract

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The present invention relates to a piperazine amide derivative as represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition thereof, and use of same as a therapeutic agent, especially as a selective Rearranged During Transfection (RET) kinase inhibitor. Ring a, ring e, X1, X2, X3, X4, R1, R2, R3, R4, R4′, R5, R5′, R6, R6′, R7, R7′, R8, m and n have the same definitions as those in the specification.

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Patent Owner(s)

  • ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Lei Zhejiang, CN 979 4055
Guo, Chenli Zhejiang, CN 1 0
Hu, Taishan Zhejiang, CN 35 359
Li, Ying Zhejiang, CN 869 31412
Qian, Wenjian Zhejiang, CN 10 6
Shi, Zhengzheng Zhejiang, CN 1 0
Yan, Sunli Zhejiang, CN 1 0
Ye, Cheng Zhejiang, CN 22 62
Zhang, Panpan Zhejiang, CN 19 22

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