GHRH or analogues thereof for use in treatment of hepatic disease

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12233107
APP PUB NO 20240091316A1
SERIAL NO

18351169

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present application relates to novel methods for preventing, slowing the progression of, or treating nonalcoholic fatty liver (NAFL), nonalcoholic steatohepatitis (NASH), and/or liver fibrosis, and/or reducing the risks of liver cancer in subjects, such as HIV-infected subjects, using a GHRH molecule, e.g., trans-3-hexenoyl-GHRH(1-44)-NH2, or a pharmaceutically acceptable salt thereof. The subjects may have particular pathological features such as liver fibrosis, a hepatic fat fraction (HFF) of at least about 10%, serum alanine aminotransferase (ALT) levels of at least about 30 U/L, and/or a NAFLD Activity Score (NAS) of at least 4 or 5.

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Patent Owner(s)

  • THE GENERAL HOSPITAL CORPORATION

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grinspoon, Steven K Weston, US 9 130

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