Bis-choline tetrathiomolybdate for treating Wilson Disease

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United States of America

PATENT NO 12233088
APP PUB NO 20230070534A1
SERIAL NO

17821786

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Abstract

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Methods for treating Wilson Disease with bis-choline tetrathiomolybdate therapy are provided. The methods may include administering 15 mg or between 30 and 90 mg of bis-choline tetrathiomolybdate once daily to a patient exhibiting NCCcorrected, alanine aminotransferase (ALT), hemoglobin, platelets, or neutrophils levels meeting specified criteria. The methods may include modifying treatment by decreasing or increasing the daily dose of bis-choline tetrathiomolybdate or discontinuing treatment for a period of time.

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Patent Owner(s)

Patent OwnerAddress
ALEXION PHARMACEUTICALS INC121 SEAPORT BOULEVARD BOSTON MA 02210

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ala, Aftab Stockholm, SE 4 9
Askari, Frederick Stockholm, SE 4 9
Bjartmar, Carl Stockholm, SE 4 9
Czlonkowska, Anna Stockholm, SE 4 9
Ferenci, Peter Stockholm, SE 6 23
Hedera, Peter Stockholm, SE 4 9
Schilsky, Michael Stockholm, SE 4 9
Weiss, Karl-Heinz Stockholm, SE 5 17

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