Crosslinker comprising genipin for use in preparation of sensing film or diffusion control film of electrochemical sensor
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United States of America
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Feb 18, 2025
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Feb 24, 2022
app pub date -
May 9, 2019
filing date -
May 9, 2019
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Abstract
The present disclosure relates to a composition for a crosslinking agent for the preparation of a sensing layer or a diffusion control layer of an electrochemical biosensor comprising genipin or a derivative thereof, in which due to the properties of genipin that can be extracted and used from plants, not only it has high biocompatibility compared to conventional crosslinking agents with high toxicity, but also it can easily confirm the progress of the reaction by measuring UV or measuring the amount of amine groups present when reacting with a compound having an amine group, for example, an electron transport medium, and additionally, it has the advantage of suppressing a rapid decrease in sensor life due to high concentration of glucose while maintaining an appropriate sensitivity to glucose.
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