Molecular DNA strand-displacement controllers for directing material expansion
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United States of America
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Feb 18, 2025
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Feb 18, 2021
app pub date -
Jan 22, 2019
filing date -
Jan 22, 2019
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Abstract
The present disclosure provides compositions and methods including modular material controllers that combine amplification with logic, translation of input signals, and response tuning to directly and precisely program dramatic material size changes. In particular, the present disclosure provides locked gels having a polymer with a nucleic acid cross link and a nucleic acid lock in a locked conformation preventing the locked gel from reacting with other nucleic acid sequences and methods of unlocking the locked gels by adding a nucleic acid key to the locked gel or by changing an inactive nucleic acid key into an active nucleic acid key with a trigger.
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