Humanized complement 5A receptor 1 antibodies and methods of use thereof

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12227587
APP PUB NO 20250002603A1
SERIAL NO

18415419

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides, among other things, two different formats of humanized antibodies against human complement component 5a receptor I. The disclosure also provides a method of treating a subject having dysfunctions of C5a/C5aR1 axis pathway, including but not limited to ANCA-associated vasculitis, comprising administering to the subject in need thereof an effective amount of antibody or a nucleic encoding an antibodies binding to C5aR1 described herein, and wherein administering results in a decrease in symptoms associated with C5a/C5aR1 associated dysfunction in the subject.

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Patent Owner(s)

  • VISTERRA, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Babcock, Gregory Waltham, US 40 138
Booth, Brian Waltham, US 21 37
Olinski, Lauren Waltham, US 4 0
Ramakrishnan, Boopathy Waltham, US 47 101
Shriver, Zachary Waltham, US 116 1834
Viswanathan, Karthik Waltham, US 86 802
Wollacott, Andrew Waltham, US 9 15

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