Nucleoside-modified mRNA-lipid nanoparticle lineage vaccine for hepatitis C virus

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12226471
APP PUB NO 20240123050A1
SERIAL NO

18310066

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Abstract

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The present invention relates to compositions and methods for inducing an adaptive immune response against Hepatitis C virus (HCV) in a subject. In some embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof. For example, in some embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding a HCV antigen, adjuvant, or a combination thereof.

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Patent Owner(s)

  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; THE JOHNS HOPKINS UNIVERSITY; VANDERBILT UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bailey, Justin R Timonium, US 4 2
Crowe,, Jr James Nashville, US 2 0
Flyak, Andrew Pasadena, US 3 0
Ray, Stuart C Lutherville, US 7 31
Shaw, George M Wallingford, US 24 86
Weissman, Drew Wynnewood, US 60 1933

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