CD19 binding molecules and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12221481
APP PUB NO 20210139585A1
SERIAL NO

16877878

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides CD19 binding molecules that specifically bind to CD19, including monospecific, bispecific and trispecific binding molecules, conjugates comprising the CD19 binding molecules, and pharmaceutical compositions comprising the CD19 binding molecules and the conjugates. The disclosure further provides methods of using the C19 binding molecules to treat diseases and disorders associated with expression of CD19. The disclosure yet further provides recombinant host cells engineered to express the CD19 binding molecules and methods of producing the CD19 binding molecules by culturing the host cells under conditions in which the CD19 binding molecules are expressed.

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Patent Owner(s)

  • NOVARTIS AG

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cebe, Regis Saint-Louis, FR 14 12
Chelur, Dattananda Cambridge, US 5 15
Granda, Brian Salisbury, US 13 248
Hong, Connie Somerville, US 14 67
Jang, Sunyoung Cambridge, US 7 64
Lu, Haihui Winchester, US 40 483
Rayo, Amy Cambridge, US 6 10

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