Saponin adjuvant and evaluation method thereof

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12221461
APP PUB NO 20210024569A1
SERIAL NO

17041175

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Abstract

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The present disclosure is related to the six isomer structures (OBI-821-1990-V1A, OBI-821-1990-V1B, OBI-821-1990-V2A, OBI-821-1990-V2B, OBI-821-1858-A, and OBI-821-1858-B) of isolated OBI-821 adjuvant and the method for evaluating the quality thereof. The method of the present disclosure adopts hydrophilic interaction liquid chromatography (HILIC) and reverse phase high performance liquid chromatography (RP-HPLC) either alone or in tandem and is able to separate the isomers of OBI-821 adjuvant in the consequent chromatography. Accordingly, the quality of OBI-821 adjuvant can be further evaluated.

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Patent Owner(s)

  • OBI PHARMA INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hsieh, Yih-Huang Taipei, TW 5 10
Lee, Wei Han Taipei, TW 3 0
Lin, Yu Chen Taipei, TW 7 42
Wang, Nan Hsuan Taipei, TW 1 0
Yu, Cheng-Der Tony Taipei, TW 24 92

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