Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (IDO1)

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United States of America

PATENT NO 12216122
APP PUB NO 20200371101A1
SERIAL NO

16879611

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present application provides stable heterobiligands made up of peptide-based IDO1 ligands and small molecule inhibitors of IDO1 and methods of use of the heterobiligands as detection, imaging, diagnostic, and therapeutic agents. The application further provides methods of manufacturing IDO1 heterobiligands, capture agents, and imaging agents.

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Patent Owner(s)

  • REGENERON PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agnew, Heather Dawn Culver City, US 15 55
Eliasen, Anders Culver City, US 10 6
Lai, Bert Tsunyin Culver City, US 12 22

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