Methods of selecting, based on polymorphisms, an inflammatory bowel disease subject for treatment with an anti-TL1A antibody

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United States of America

PATENT NO 12215147
APP PUB NO 20230018729A1
SERIAL NO

17409639

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are methods, systems, and kits for selecting a patient for treatment with a therapeutic agent based on a presence of a genotype associated with a positive therapeutic response to the therapeutic agent. The therapeutic agent, in some embodiments, is an inhibitor of TL1A activity or expression, such as for example, an anti-TL1A antibody.

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Patent Owner(s)

  • PROMETHEUS BIOSCIENCES, INC.; CEDARS SINAI MEDICAL CENTER

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bilsborough, Janine Los Angeles, US 79 1390
Kruidenier, Laurens San Diego, US 7 26
Li, Dalin Los Angeles, US 18 48
McGovern, Dermot P Los Angeles, US 37 190
Sabripour, Mahyar San Diego, US 5 5

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