Method of treating fatty acid oxidation disorders using omega3/omega6 unsaturated or branched chain fatty acids
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United States of America
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Feb 4, 2025
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Nov 18, 2021
app pub date -
Jul 28, 2021
filing date -
Jul 28, 2021
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Abstract
A method of treating medium chain acyl-CoA dehydrogenase deficiency, very long chain acyl-CoA dehydrogenase deficiency, long chain hydroxyacyl-CoA dehydrogenase deficiency, trifunctional protein deficiency, or CPT II deficiency in a patient is provided comprising administering to the patient a therapeutic amount of a triglyceride or other conjugated fatty acid that bypasses or leads to an intermediate that bypasses the deficient enzyme. Amino acid-conjugated fatty acids also are provided as well as compositions comprising the amino acid-conjugated fatty acids.
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