Compositions and methods for broad-spectrum antiviral therapy

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United States of America

PATENT NO 12213955
APP PUB NO 20200338032A1
SERIAL NO

16757312

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Abstract

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AM580 and structurally related compounds have been found to be useful in treating infection by a wide range of RNA and DNA viruses, and also in reducing associated inflammation. This activity is independent of RAR-α signaling, and is not a result of activation of the hosts innate immune response. Broad antiviral activity of AM580 and structurally related compounds is a due to modulation of lipogenesis so as to correct disregulation of this pathway in virus-infected cells, via inhibition of nSREPBP.

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Patent Owner(s)

  • VERSITECH LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chan, Fuk Woo Jasper Kowloon, HK 9 2
Chu, Hin Sai Ying Pun, HK 4 0
Lau, Johnson Yiu-Nam Houston, US 56 35
Yuan, Shuofeng Shek Tong Tsui, HK 9 1
Yuen, Kwok Yung Pok Fu Lam, HK 33 133

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