Methods and systems for analysis of samples containing particles used for gene delivery
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United States of America
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Jan 28, 2025
Grant Date -
Feb 15, 2024
app pub date -
Oct 24, 2023
filing date -
Oct 24, 2023
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Abstract
Embodiments disclosed include systems, devices, and methods for analysis of samples containing particles used for gene delivery to determine a quality of the sample and/or an indication that the gene delivery particles are in a full, partial, and/or empty state. The present disclosure also relates to determining a protein and/or NA content in samples with known proportions of gene delivery particles in a full, partial, and/or empty state and based on the determination, establish a relationship between NA content and proportions of gene delivery particles in a full state. The present disclosure also relates to using such an established relationship to predict a proportion of the gene delivery particles in a full, partial, and/or empty state in test samples having the gene delivery particles in an unknown state.
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