Apparatus and methods relating to freezing at least part of a biological sample
Number of patents in Portfolio can not be more than 2000
United States of America
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Jan 28, 2025
Grant Date -
Oct 22, 2020
app pub date -
Dec 20, 2018
filing date -
Dec 20, 2018
priority date (Note) -
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Abstract
Disclosed is a device for use in freezing at least part of a biological sample in a receptacle, e.g. a vial or a cryopreservation bag, the device comprising: a base; and a receptacle holder comprising: a first part configured to, with the receptacle held by the receptacle holder during cooling of the base using a cooler device, withdraw heat energy from a first portion of the receptacle at a first heat withdrawal rate; and a second part configured such that, with the receptacle held by the receptacle holder during cooling of the base using the cooler device, a second heat withdrawal rate of heat energy withdrawal from a second portion of the receptacle via the second part is less than the first heat withdrawal rate. A temperature gradient may be established in the sample to enable progressive solidification to occur in the sample. A receptable for use in freezing a biological sample, and a freezing method are disclosed also.
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