Neutralizing antibodies to GP120 and their use

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United States of America Patent

PATENT NO 12202886
APP PUB NO 20230060304A1
SERIAL NO

17855553

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Abstract

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Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Connors, Mark Bethesda, US 28 135
Huang, Jinghe Derwood, US 10 25
Ishida, Elise Chevy Chase, US 8 1
Kang, Byong Ha Rockville, US 5 2
Kwong, Peter Washington, US 55 200
Mascola, John Rockville, US 51 109
Zheng, Anqi Boyds, US 6 1
Zhou, Tongqing Boyds, US 44 202

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