Methods for heat-assisted enzyme digestion

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United States of America Patent

PATENT NO 12202857
APP PUB NO 20210347814A1
SERIAL NO

17314541

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Abstract

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The present disclosure relates to a method of digesting a sample comprising protein, the method comprising: adding the sample to an apparatus containing a buffer and a solid support surface comprising a surface coating, wherein the surface coating immobilizes enzyme while reducing undesired interactions between the sample and the solid support surface; immobilizing enzymes on the surface coating for digestion of the protein of the sample; and heating the sample to complete a heat-assisted digestion of the protein.

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Patent Owner(s)

Patent OwnerAddress
WATERS TECHNOLOGIES CORPORATION34 MAPLE STREET MILFORD MA 01757

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boardman, Anna Watertown, US 9 5
Lauber, Matthew A North Smithfield, US 80 60
Li, Wenjing Shrewsbury, US 58 505
Muriithi, Beatrice Attleboro, US 11 1

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