Benzothia(di)azepine compounds and their use as bile acid modulators

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United States of America Patent

PATENT NO 12202809
APP PUB NO 20240109854A1
SERIAL NO

18328658

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Abstract

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The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.

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Patent Owner(s)

Patent OwnerAddress
ALBIREO ABGOTHENBURG GOTHENBURG VASTRA GOTALAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gillberg, Per-Göran Åsbro, SE 69 1949
Kulkarni, Santosh S Bangalore, IN 48 762
Starke, Ingemar Gothenburg, SE 78 2308

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