Adeno-associated virus compositions for restoring HBB gene function and methods of use thereof

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United States of America Patent

PATENT NO 12201657
APP PUB NO 20190134118A1
SERIAL NO

16163061

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Abstract

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Provided herein are adeno-associated virus (AAV) compositions for correcting a mutation in a beta globin gene (HBB) gene and methods of using the same to correct an HBB gene mutation in a cell. Also provided are packaging systems for making the adeno-associated virus compositions.

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CITY OF HOPE1500 E DUARTE ROAD DUARTE CA 91010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BenHajSalah, Marwa Duarte, US 1 0
Chatterjee, Saswati Altadena, US 29 805
Dollive, Serena Nicole Waltham, US 11 12
McSwiggen, James Anthony Arlington, US 12 119
Prout, Jaime Michelle Hudson, US 4 2
Seymour, Albert Barnes Westborough, US 15 13
Smith, Laura Jane Westford, US 18 345
St, Martin Thia Baboval Lunenburg, US 4 0
Wong,, Jr Kamehameha K Altadena, US 4 72
Wright, Jason Boke Concord, US 11 12

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