Methods to determine KDM1A target engagement and chemoprobes useful therefor

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United States of America

PATENT NO 12195783
APP PUB NO 20220389478A1
SERIAL NO

17644604

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Abstract

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The invention relates to methods to determine KDM1A target engagement and chemoprobes useful therefor. In particular, the invention relates to non-peptidic KDM1A chemoprobes carrying a tag or label that can be used to assess KDM1A target engagement in cells and tissues. These chemoprobes can also be used to identify KDM1A interacting factors and analyze expression levels of KDM1A.

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Patent Owner(s)

Patent OwnerAddress
ORYZON GENOMICS S AMADRID

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carceller, González Elena Sant Cugat, ES 9 10
Maes, Tamara Castelldefels, ES 33 251
Mascaro, Crusat Cristina Barcelona, ES 5 3
Ortega, Muñoz Alberto Barcelona, ES 19 202

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