Substituted pyrazolo piperidine carboxylic acids

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12195448
APP PUB NO 20230265072A1
SERIAL NO

18134378

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Abstract

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The invention relates to substituted pyrazolo piperidine carboxylic acids, their salts and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular and cardiac diseases, preferably heart failure with reduced and preserved ejection fraction (HFrEF, HFmrEF and HFpEF), hypertension (HTN), peripheral arterial diseases (PAD, PAOD), cardio-renal and kidney diseases, preferably chronic and diabetic kidney disease (CKD and DKD), cardiopulmonary and lung diseases, preferable pulmonary hypertension (PH), and other diseases, preferably neurodegenerative diseases and different forms of dementias, fibrotic diseases, systemic sclerosis (SSc), sickle cell disease (SCD), wound healing disorders such as diabetic foot ulcer (DFU).

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Patent Owner(s)

  • BAYER AKTIENGESELLSCHAFT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boultadakis-Arapinis, Melissa Düsseldorf, DE 6 0
Candish, Lisa Wuppertal, DE 6 0
Collin-Kröpelin, Marie-Pierre Weil am Rhein, DE 12 29
Dieskau, Andre Wuppertal, DE 6 0
Dietz, Lisa Wuppertal, DE 38 95
Hofmeister, Lucas Hudson Berlin, DE 10 3
Mathar, Ilka Düsseldorf, DE 8 3
Mondritzki, Thomas Essen, DE 23 78
Ortega, Hernandez Nuria Wuppertal, DE 8 1
Sandner, Peter Wuppertal, DE 36 120
Schmeck, Carsten Mülheim, DE 72 425
Stellfeld, Timo Berlin, DE 28 34
Vakalopoulos, Alexandros Hilden, DE 83 431
Webster, Robert Alan Berlin, DE 16 11
Wunder, Frank Wuppertal, DE 137 2089

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