Compositions and methods for reducing oxidative damage

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12194053
APP PUB NO 20240041907A1
SERIAL NO

18204225

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Abstract

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Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water, adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION INCUOFL INNOVATION & COMMERCIALIZATION 300 EAST MARKET STREET SUITE 300 LOUISVILLE KY 40202

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gobin, Andrea S Pearland, US 8 26
O'Toole, Martin G Louisville, US 11 12
Tezel, Tongalp H New York, US 12 35

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