Development and characterization of f-gelatin electrospun scaffolds for cardiac tissue modeling
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United States of America
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Jan 7, 2025
Grant Date -
Nov 23, 2023
app pub date -
Apr 18, 2023
filing date -
Apr 18, 2023
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Abstract
Cardiac tissue-on-a-chip platforms aimed at mimicking human cardiac tissue structures, are valuable tools to model, and serve as preclinical platforms for drug testing or therapies for cardiac repair. We have developed three types of electrospun scaffolds including furfuryl gelatin (f-gelatin) alone, with polycaprolactone (PCL) in the ratio of f-gelatin and PCL (1:1), and coaxial scaffolds with PCL (core) and f-gelatin (sheath). Scaffolds were developed through single nozzle electrospinning and coaxial electrospinning, respectively, to serve as scaffolds for cardiac tissue-on-a-chip platforms.
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International Classification(s)
- C08J:WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTE....
- D01D:MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE....
- B29C:SHAPING OR JOINING OF PLASTICS; SHAPING OF SUBSTAN....
- C07D:HETEROCYCLIC COMPOUNDS
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- D06M:TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D0....
- A61L:METHODS OR APPARATUS FOR STERILISING MATERIALS OR ....
- C08L:COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- D01F:CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL....
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