Preparation of ceramide conjugates and derivatives of sphingolipid analogues

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United States of America

PATENT NO 12187817
APP PUB NO 20230374076A1
SERIAL NO

18363810

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Abstract

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The preparation of water dispersible ceramide conjugates and derivatives of sphingolipid analogues is described. The conjugates and analogues are prepared by reacting a succinimidyl carbonate of a β-Ala derivative with the primary amine of a functionalised spacer. Despite their dispersibility in water, the ceramide conjugates and derivatives of sphingolipid analogues spontaneously incorporate in to the plasma membranes of cells.

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Patent Owner(s)

  • KODE BIOTECH LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bovin, Nicolai Vladimirovich Moscow, RU 16 8
Henry, Stephen Micheal Auckland, NZ 26 21
Tuzikov, Alexander Borisovich Moscow, RU 13 8

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