Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12186317
APP PUB NO 20230381177A1
SERIAL NO

18447130

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Abstract

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The present disclosure discloses compounds capable of modulating the activity of α-amino-β-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NAD+ biosynthesis, e.g., metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, kidney diseases, and diseases associated with ageing. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament.

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Patent Owner(s)

  • TES PHARMA S.R.L.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Franco Francesca Perugia, IT 5 1
Giacche, Nicola Perugia, IT 2 1
Liscio, Paride Perugia, IT 3 1
Pellicciari, Roberto Perugia, IT 87 958

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