Reagents for detection of chimeric antigen receptor cells
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United States of America
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Dec 31, 2024
Grant Date -
Dec 2, 2021
app pub date -
Apr 9, 2021
filing date -
Apr 9, 2021
priority date (Note) -
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Abstract
The invention is directed to a method for preparing a detection reagent for CAR expressing cells according to general formula (I)
- wherein D is a detection moiety, S a spacer unit and X a polypeptide comprising 10 to 80 amino acids and a N3 group, which binds to the antigen binding domain of a chimeric antigen receptor of a cell and m=4-200, characterized in reacting p detection moieties D with a spacer S according to general formula (II)
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