Targeted extracellular vesicles for delivery of therapeutics

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12180481
APP PUB NO 20240150763A1
SERIAL NO

18275591

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Abstract

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The present invention is directed to Saccharomyces-generated extracellular vesicles (EVs) comprising a foreign RNA molecule or protein and at least one foreign membrane surface exposed ligand that specifically binds to a target receptor displayed on a target cell. The present invention also relates to methods of making and using these Saccharomyces-generated EVs for targeted gene silencing. The present invention also relates to fusion proteins comprising a Saccharomyces extracellular vesicle anchor protein and a second peptide designed to bind to cell-specific receptors.

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Patent Owner(s)

  • MERCURY BIO, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pertzev, Alexander Santa Fe, US 2 0
Sayre, Richard Los Alamos, US 20 14
Vinogradova-Shah, Tatiana Rochester, US 10 1

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