Antigen binding molecule formats

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United States of America

PATENT NO 12180272
APP PUB NO 20220235126A1
SERIAL NO

17666107

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Abstract

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Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.

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Patent Owner(s)

  • REGENERON PHARMACEUTICALS, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Davis, Samuel New York, US 108 2593
Lin, Chia-Yang Scarsdale, US 65 112
Liu, Nina Chappaqua, US 12 3
Murphy, Andrew Croton-on-Hudson, US 106 971
Patel, Supriya Elmsford, US 16 125
Pyles, Erica New City, US 32 59
Rosconi, Michael New City, US 13 2
Smith, Eric New York, US 253 3725
Zhang, Tong New Rochelle, US 441 7760

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