Methods for extracting proteins from a blood-based material
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United States of America
Stats
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Dec 31, 2024
Grant Date -
Aug 26, 2021
app pub date -
May 13, 2021
filing date -
May 13, 2021
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Methods of producing multiple protein products from blood-based materials including alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins are described herein. The inventive methods include steps of: salt fractionation, chromatography, ultrafiltration, diafiltration, solvent-detergent treatment, and sterile filtration. Advantageously, the inventive methods are simple and produce alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins in high yields. The sequence of process steps can be selected to obtain multiple products from various in-process materials, such as supernatants, pastes, chromatography flow-though, and chromatography washes.
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International Classification(s)
- 2021 Application Filing Year
- A61K Class
- 21749 Applications Filed
- 5923 Patents Issued To-Date
- 27.24 % Issued To-Date
Cited Art Landscape
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- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 1 Age
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