Electronic circuits for analyzing electrogenic cells and related methods

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12174140
APP PUB NO 20200292482A1
SERIAL NO

16760723

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Abstract

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Methods and systems for monitoring the activity of electrogenic networks are described. One representative system includes an array of electrode coupled to an analyzer having a stimulator and a receiver. The electrode is placed in contact with an electrogenic cell. The electrodes can be shaped as nanowires, tubes, cavities and/or cones. The analyzer may be configured to operate in a voltage stimulation mode, in which the cells are stimulated via voltages and monitored via current, or in a current stimulation mode, in which the cells are stimulated via currents and monitored via voltages. The analyzers may be arranged as single-stage amplifiers, and may include a feedback loop shared between the stimulation signal path and the sensing signal path. The feedback loop may be arranged to provide overlapping stimulation and sensing of the electrogenic network's cells.

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Patent Owner(s)

  • PRESIDENT AND FELLOWS OF HARVARD COLLEGE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abbott, Jeffrey T Cambridge, US 11 37
Ham, Donhee Cambridge, US 34 453
Krenek, Keith Cambridge, US 1 5
Park, Hongkun Cambridge, US 56 1972
Wu, Wenxuan Cambridge, US 13 34
Ye, Tianyang Cambridge, US 8 29

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