Polypeptide variants and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12173076
APP PUB NO 20200181277A1
SERIAL NO

16482747

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Abstract

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As described herein are polypeptides and antibodies having an Fc region and an antigen binding region where the Fc region has an Fc-Fc-enhancing mutation and a C1q binding-enhancing mutation providing for polypeptides or antibodies with increased CDC activity and/or agonistic activity.

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Patent Owner(s)

Patent OwnerAddress
GENMAB B V3584 CT UTRECHT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beurskens, Frank Utrecht, NL 46 270
De, Jong Rob Utrecht, NL 20 56
Diks, Annieck M Gouda, NL 1 3
Overdijk, Marije Utrecht, NL 22 96
Parren, Paul Odijk, NL 234 3032
Schuurman, Janine Diemen, NL 116 1580
Strumane, Kristin Werkhoven, NL 19 72

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