Human-derived anti-(poly-GA) dipeptide repeat (DPR) antibody

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12162952
APP PUB NO 20220153874A1
SERIAL NO

17050353

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Abstract

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Provided are novel dipeptide repeat (DPR) specific antibodies (e.g., human-derived antibodies) as well as synthetic variants and biotechnological derivatives thereof, capable of binding C9orf72 poly-glycine-alanine DPRs, as well as methods and uses related thereto. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.

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Patent Owner(s)

Patent OwnerAddress
BIOGEN MA INC250 BINNEY STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arndt, Joseph Walter Swampscott, US 3 0
Dalkilic-Liddle, Isin Watertown, US 4 0
Grimm, Jan Dübendorf, CH 92 618
Montrasio, Fabio Schindellegi, CH 18 31
Rushe, Mia Marie Everett, US 5 25

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