Methods for forming a nanopore in a lipid bilayer

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United States of America

PATENT NO 12158462
APP PUB NO 20240011970A1
SERIAL NO

18471506

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Abstract

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A method of forming a nanopore in a lipid bilayer is disclosed. A nanopore forming solution is deposited over a lipid bilayer. The nanopore forming solution has a concentration level and a corresponding activity level of pore molecules such that nanopores are substantially not formed un-stimulated in the lipid bilayer. Formation of a nanopore in the lipid bilayer is initiated by applying an agitation stimulus level to the lipid bilayer. In some embodiments, the concentration level and the corresponding activity level of pore molecules are at levels such that less than 30 percent of a plurality of available lipid bilayers have nanopores formed un-stimulated therein.

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Patent Owner(s)

Patent OwnerAddress
ROCHE SEQUENCING SOLUTIONS INCPLEASANTON CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Roger J A Saratoga, US 65 158
Davis, Randall Pleasanton, US 56 747

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