Prevention of disulfide bond reduction during recombinant production of polypeptides

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12145997
APP PUB NO 20240301080A1
SERIAL NO

18648209

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The invention concerns methods for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
GENENTECH INCCALIFORNIA USA CALIFORNIA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hewitt, Daniel P Sunnyvale, US 16 253
Kao, Yung-Hsiang San Mateo, US 27 637
Laird, Michael W San Ramon, US 41 488
Schmidt, Melody Trexler Danville, US 16 253
Wong, Rita L Redwood City, US 23 909

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 May 19, 2028
7.5 Year Payment $3600.00 $1800.00 $900.00 May 19, 2032
11.5 Year Payment $7400.00 $3700.00 $1850.00 May 19, 2036
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00