Bacterial strain for releasing a recombinant protein in a fermentation method
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United States of America
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Nov 12, 2024
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N/A
app pub date -
Jul 6, 2018
filing date -
Jul 6, 2018
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A bacterial strain suitable for expressing recombinant proteins contains an open reading frame which codes for a recombinant protein, under control of a functional promoter. The bacterial strain contains an open reading frame which codes for a muted peptidologycan-associated lipoprotein (PAL protein), under control of a functional promoter, wherein the PAL protein is muted such that it contains no membrane anchor for the outer cell membrane of the bacterial strain. A plasmid codes for a recombinant protein. Fermentative production of recombinant protein is facilitated by using the bacterial strain, with increased product yields in the culture residue without leading to a substantial die-off of the bacterial cells.
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International Classification(s)
- 2018 Application Filing Year
- C12R Class
- 243 Applications Filed
- 95 Patents Issued To-Date
- 39.10 % Issued To-Date
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- C12R Class
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