Apparatus for efficient genetic modification of cells
Number of patents in Portfolio can not be more than 2000
United States of America
Stats
-
Nov 12, 2024
Grant Date -
Mar 2, 2023
app pub date -
Sep 16, 2022
filing date -
Sep 16, 2022
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A device for treatment of cells with particles is disclosed. The device includes a semi-permeable membrane positioned between two plates, the first plate defining a first flow chamber and comprising a port, a flow channel, a transverse port, and a transverse flow channel, the first flow chamber constructed and arranged to deliver fluid in a transverse direction along the first side of the semi-permeable membrane, the second plate defining a second flow chamber and comprising a port. A method for transducing cells is disclosed. The method includes introducing a fluid with cells and viral particles into a flow chamber adjacent a semi-permeable membrane such that the cells and the viral particles are substantially evenly distributed on the semi-permeable membrane. The method also includes introducing a recovery fluid to suspend the cells and the viral particles, and separating the cells from the viral particles. A method of activating cells is disclosed.
First Claim
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Family
International Classification(s)
- 2022 Application Filing Year
- A61K Class
- 20288 Applications Filed
- 3818 Patents Issued To-Date
- 18.82 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 1 Age
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