Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains

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United States of America

PATENT NO 12139525
APP PUB NO 20220073588A1
SERIAL NO

17366565

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Abstract

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The present invention is directed to a novel targeted heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc fusion protein and an antigen binding domain Fc fusion proteins. In some instances, the antigen binding domain binds to CD8, NKG2A, or NKG2D.

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Patent Owner(s)

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XENCOR INC111 WEST LEMON AVENUE MONROVIA CA 91016

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernett, Matthew J Monrovia, US 82 1810
Desjarlais, John Altadena, US 142 2835
Diaz, Juan Anaheim Hills, US 34 239
Schubbert, Suzanne Long Beach, US 11 15
Varma, Rajat Monrovia, US 31 158

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