Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders

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United States of America

PATENT NO 12139497
APP PUB NO 20230287005A1
SERIAL NO

18124427

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Abstract

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Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R12 or R13 on the A group is an aryl, heteroaryl or heterocycle (R32) are provided. The inhibitors of Factor D described herein reduce the excessive activation of complement.

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Patent Owner(s)

Patent OwnerAddress
ACHILLION PHARMACEUTICALS INC300 GEORGE STREET NEW HAVEN CT 06115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agarwal, Atul Hamden, US 84 2110
Chen, Dawei Guilford, US 145 2233
Deshpande, Milind Madison, US 99 2289
Gadhachanda, Venkat Rao Hamden, US 61 1826
Hashimoto, Akihiro Branford, US 142 2601
Pais, Godwin Hamden, US 75 1908
Phadke, Avinash S Branford, US 57 1752
Wang, Qiuping Bethany, US 78 1844
Wang, Xiangzhu Branford, US 86 2071
Wiles, Jason Allan Madison, US 102 2022

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