Antibody variable domains targeting the NKG2D receptor

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United States of America

PATENT NO 12129300
APP PUB NO 20240067735A1
SERIAL NO

18501419

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Abstract

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Antibody heavy chain variable domains that can be paired with antibody light chain variable domains to form an antigen-binding site targeting the NKG2D receptor on natural killer cells are described. Proteins comprising an NKG2D antigen-binding site, pharmaceutical compositions and therapeutic methods thereof, including for the treatment of cancer, are also described.

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Patent Owner(s)

  • DRAGONFLY THERAPEUTICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Gregory P Medford, US 50 251
Cheung, Ann F Lincoln, US 57 242
Grinberg, Asya Lexington, US 126 552
Haney, William Wayland, US 56 256
Lunde, Bradley M Lebanon, US 43 196
Prinz, Bianka Lebanon, US 116 486

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