Autofocus sample imaging apparatus and method
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United States of America Patent
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Oct 22, 2024
Grant Date -
Dec 2, 2021
app pub date -
Sep 10, 2019
filing date -
Sep 10, 2018
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Abstract
We describe in this application systems and methods for autofocusing in imaging mass spectrometry. The present application describes improvements over current IMS and IMC apparatus and methods through an autofocus component including a plurality of apertures in the autofocus system, such as a plurality of apertures arranged in 2 dimensions. As a plurality of apertures is used, the autofocus system provides redundancy in the event that measurement of focus on the sample from the illuminating radiation passed through one or more of the apertures fails so as to reduce the number of unsuccessful autofocus attempts.
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