IL-21 polypeptides and targeted constructs

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United States of America Patent

PATENT NO 12122827
APP PUB NO 20230357343A1
SERIAL NO

18307477

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Abstract

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The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.

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Patent Owner(s)

Patent OwnerAddress
ASHER BIOTHERAPEUTICS INC650 GATEWAY BLVD SUITE 100 SOUTH SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Djuretic, Ivana Pacifica, US 15 67
Greer, Renee L Pacifica, US 3 4
Kang, Byong San Francisco, US 3 4
Liu, David Pacifica, US 263 5445
Nguyen, Henry C San Francisco, US 5 22
Yeung, Yik Andy South San Francisco, US 28 242

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