GIP receptor agonist peptide compounds and uses thereof

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United States of America Patent

PATENT NO 12122815
SERIAL NO

17279266

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Abstract

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The present disclosure provides GIP receptor agonist peptide compounds having an activating action on GIP receptors and use of the GIP receptor agonist peptide as a medicament for the treatment and/or prevention of diabetes, obesity, emesis, or a symptom or condition associated with diabetes, obesity, or emesis. Specifically, a GIP receptor agonist peptide containing a sequence represented by the formula (I) or a salt thereof, and a medicament comprising the same are provided. Formula I: P1-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-A25-A26-A27-A28-A29-A30-A31-A32-A33-A34-A35-A36-A37-A38-A39-A40-A41-P2 (SEQ ID NO: 4), or a salt thereof, wherein each symbol is as defined herein, with the proviso that the GIP receptor agonist peptide does not have an amino acid sequence as provided in SEQ ID NOs: 328-893.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITEDOSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adachi, Mari Fujisawa, JP 8 13
Asami, Taiji Fujisawa, JP 26 143
Bhat, Abhijit Suresh Cambridge, US 9 108
Cole, Derek Cecil San Diego, US 49 354
Flinspach, Mack San Diego, US 13 48
Imoto, Hiroshi Fujisawa, JP 73 515
Kanematsu, Yoko Fujisawa, JP 5 7
Niida, Ayumu Fujisawa, JP 10 13
Nishizawa, Naoki Fujisawa, JP 22 173
Scorah, Nick San Diego, US 2 1

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