Parallel microfluidic device for high throughput cell assays in microdroplets

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United States of America Patent

PATENT NO 12121899
APP PUB NO 20210308681A1
SERIAL NO

17261992

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Abstract

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A high throughput microdroplet-based system for single cell assays in microdroplets is provided. The system integrates parallel devices and switches to enable simultaneous analysis of different cells or cell combinations, or different assay conditions, on a single microfluidic chip. Interconnections between the inlets of individual devices on a common chip enable simultaneous screening of the effect of different combinations of drugs on single cells. The use of an oil inlet and microchannels with matched total flow resistance allows the synchronous generation of droplets with the same dimensions and/or volumes.

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Patent Owner(s)

  • NORTHEASTERN UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kang, Wenjing Waltham, US 13 65
Konry, Tania Boston, US 16 27
Sarkar, Saheli Boston, US 7 8

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